Search results for "Libraries"
showing 10 items of 255 documents
First observation of a baryonic Bc+ decay
2014
A baryonic decay of the $B_c^+$ meson, $B_c^+\to J/\psi p\overline{p}\pi^+$, is observed for the first time, with a significance of $7.3$ standard deviations, in $pp$ collision data collected with the LHCb detector and corresponding to an integrated luminosity of $3.0$ fb$^{-1}$ taken at center-of-mass energies of $7$ and $8$ $\mathrm{TeV}$. With the $B_c^+\to J/\psi \pi^+$ decay as normalization channel, the ratio of branching fractions is measured to be \begin{equation*} \frac{\mathcal{B}(B_c^+\to J/\psi p\overline{p}\pi^+)}{\mathcal{B}(B_c^+\to J/\psi \pi^+)} = 0.143^{\,+\,0.039}_{\,-\,0.034}\,(\mathrm{stat})\pm0.013\,(\mathrm{syst}). \end{equation*} The mass of the $B_c^+$ meson is dete…
Bottom-up approach within the electroweak effective theory: Constraining heavy resonances
2020
The LHC has confirmed the existence of a mass gap between the known particles and possible new states. Effective field theory is then the appropriate tool to search for low-energy signals of physics beyond the Standard Model. We adopt the general formalism of the electroweak effective theory, with a non-linear realization of the electroweak symmetry breaking, where the Higgs is a singlet with independent couplings. At higher energies we consider a generic resonance Lagrangian which follows the above-mentioned non-linear realization and couples the light particles to bosonic heavy resonances with $J^P=0^\pm$ and $J^P=1^\pm$. Integrating out the resonances and assuming a proper short-distance…
Testing WWγ vertex in radiative muon decay
2019
Large numbers of muons will be produced at facilities developed to probe the lepton-flavor-violating process μ→eγ. We show that by constructing a suitable asymmetry, radiative muon decay μ→eγνμν̄e can also be used to test the WWγ vertex at such facilities. The process has two missing neutrinos in the final state, and upon integrating their momenta the partial differential decay rate shows no radiation-amplitude zero. However, we establish that an easily separable part of the normalized differential decay rate that is odd under the exchange of photon and electron energies does have a zero in the case of the standard model (SM). This new type of zero has hitherto not been studied in the liter…
De novo design of protein kinase inhibitors by in silico identification of hinge region-binding fragments.
2013
Protein kinases constitute an attractive family of enzyme targets with high relevance to cell and disease biology. Small molecule inhibitors are powerful tools to dissect and elucidate the function of kinases in chemical biology research and to serve as potential starting points for drug discovery. However, the discovery and development of novel inhibitors remains challenging. Here, we describe a structure-based de novo design approach that generates novel, hinge-binding fragments that are synthetically feasible and can be elaborated to small molecule libraries. Starting from commercially available compounds, core fragments were extracted, filtered for pharmacophoric properties compatible w…
Improving the kinetic couplings in lattice nonrelativistic QCD
2019
We improve the non-relativistic QCD (NRQCD) action by comparing the dispersion relation to that of the continuum through $\mathcal{O}(p^6)$ in perturbation theory. The one-loop matching coefficients of the $\mathcal{O}(p^4)$ kinetic operators are determined, as well as the scale at which to evaluate $\alpha_s$ in the $V$-scheme for each quantity. We utilise automated lattice perturbation theory using twisted boundary conditions as an infrared regulator. The one-loop radiative corrections to the mass renormalisation, zero-point energy and overall energy-shift of an NRQCD $b$-quark are also found. We also explore how a Fat$3$-smeared NRQCD action and changes of the stability parameter $n$ aff…
Chloroplast genomes of Rubiaceae: Comparative genomics and molecular phylogeny in subfamily Ixoroideae.
2020
In Rubiaceae phylogenetics, the number of markers often proved a limitation with authors failing to provide well-supported trees at tribal and generic levels. A robust phylogeny is a prerequisite to study the evolutionary patterns of traits at different taxonomic levels. Advances in next-generation sequencing technologies have revolutionized biology by providing, at reduced cost, huge amounts of data for an increased number of species. Due to their highly conserved structure, generally recombination-free, and mostly uniparental inheritance, chloroplast DNA sequences have long been used as choice markers for plant phylogeny reconstruction. The main objectives of this study are: 1) to gain in…
Dark matter stability and Dirac neutrinos using only Standard Model symmetries
2020
We provide a generic framework to obtain stable dark matter along with naturally small Dirac neutrino masses generated at the loop level. This is achieved through the spontaneous breaking of the global $U(1)_{B-L}$ symmetry already present in Standard Model. The $U(1)_{B-L}$ symmetry is broken down to a residual even $\mathcal{Z}_n$; $n \geq 4$ subgroup. The residual $\mathcal{Z}_n$ symmetry simultaneously guarantees dark matter stability and protects the Dirac nature of neutrinos. The $U(1)_{B-L}$ symmetry in our setup is anomaly free and can also be gauged in a straightforward way. Finally, we present an explicit example using our framework to show the idea in action.
Gestión y liderazgo del talento: las claves del éxito empresarial
2021
Desde hace ya unas décadas, se está trabajando con profundidad en la investigación científica sobre la evidencia en las empresas de la gestión del talento. A nivel profesional, ya han sido muchas organizaciones las que han dado el salto cualitativo hacia una nueva manera de enfocar los recursos humanos (RR. HH.). Principalmente porque esta nueva perspectiva está más vinculada tanto al negocio como a los objetivos empresariales, además de ser más aceptada por la mayoría de los profesionales. Desde los orígenes de la guerra del talento por Mckinsey hasta la actualidad, la investigación está analizando el papel de la gestión del talento en los resultados organizativos. En este sentido, Luna (2…
Enumerating higher-dimensional operators with on-shell amplitudes
2020
We establish a simple formula for the minimal dimension of operators leading to any helicity amplitude. It eases the systematic enumeration of independent operators from the construction of massless non-factorizable on-shell amplitudes. Little-group constraints can then be solved algorithmically for each helicity configuration to extract a complete set of spinor structures with lowest dimension. Occasionally, further reduction using momentum conservation, on-shell conditions and Schouten identities is required. A systematic procedure to account for the latter is presented. Dressing spinor structures with dot products of momenta finally yields the independent Lorentz structures for each heli…
Measurement of the charge asymmetry in top quark pair production in pp collisions at root s=7 TeV using the ATLAS detector
2012
A measurement of the top-antitop production charge asymmetry A[subscript C] is presented using data corresponding to an integrated luminosity of 1.04 fb[superscript −1] of pp collisions at s√=7 TeV collected by the ATLAS detector at the LHC. Events are selected with a single lepton (electron or muon), missing transverse momentum and at least four jets of which at least one jet is identified as coming from a b-quark. A kinematic fit is used to reconstruct the t[bar over t] event topology. After background subtraction, a Bayesian unfolding procedure is performed to correct for acceptance and detector effects. The measured value of A[subscript C] is A[subscript C]=−0.019±0.028 (stat.)±0.024 (s…